Does it have an internal fan ? I don't think any of these do. Yes, there are many people that opened these up (check YouTube.com) and removed the drive when the USB to HD adaptor dies or the AC adaptor plug breaks, etc, etc.
I can't see how just tipping it over would make the HD go bad, but you never know. Usually it's just a zig.
If the plate is hitting the head... it's toast. I can only thing of an internal fan getting out of alignment and make a racket.
The screws are hidden under all sorts of lables or some just snap together.
They make it difficult to disassemble. Plus they may have those anti-removal torque bolts that require special tips.